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Search by protein name, UniProt number, IPI number, or 15 AA P-site sequence.
Updated: 2017 Aug. 1
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Warning
– Occasionally the phosphosites shown below in more divergent species may be slightly mis-aligned with our algorithm and the calculated Conservation Score may be higher than shown.
Phosphosite
Conservation Score
Human Protein:
FHIT
All Species:
23.94
Human Site:
T67
Identified Species:
47.88
UniProt:
P49789
Number Species:
11
Phosphosite Substitution
Charge Score:
-0.09
Phosphosite
Sequences
Species
Species
Scientific Name
UniProt ID
NCBI Ref Seq ID
AA#
Mr(Da)
P-Site
-7
-6
-5
-4
-3
-2
-1
0
1
2
3
4
5
6
7
Human
Homo sapiens
P49789
NP_002003.1
147
16858
T67
Q
T
T
Q
R
V
G
T
V
V
E
K
H
F
H
Chimpanzee
Pan troglodytes
XP_001156390
66
7556
Rhesus Macaque
Macaca mulatta
XP_001094642
149
17140
T67
Q
V
T
Q
R
V
G
T
V
V
E
K
H
F
H
Dog
Lupus familis
Cat
Felis silvestris
Mouse
Mus musculus
O89106
150
17216
T67
Q
V
T
Q
R
V
G
T
V
V
E
K
H
F
Q
Rat
Rattus norvegicus
Q9JIX3
150
17329
T67
Q
V
T
Q
R
V
G
T
V
V
E
K
H
F
Q
Wallaby
Macropus eugenll
Platypus
Ornith. anatinus
XP_001505882
135
15318
N50
Q
T
T
Q
K
V
G
N
V
V
E
K
H
F
N
Chicken
Gallus gallus
XP_414409
148
16862
N66
R
T
A
Q
R
V
G
N
A
V
E
K
H
F
C
Frog
Xenopus laevis
NP_001088719
148
16886
S67
T
T
V
Q
K
V
A
S
V
V
E
S
H
F
G
Zebra Danio
Brachydanio rerio
NP_957034
150
17218
S68
M
T
T
Q
R
V
S
S
Q
I
E
K
H
F
Q
Tiger Blowfish
Takifugu rubipres
Fruit Fly
Dros. melanogaster
Honey Bee
Apis mellifera
Nematode Worm
Caenorhab. elegans
Sea Urchin
Strong. purpuratus
Poplar Tree
Populus trichocarpa
XP_002326061
209
23713
S122
F
T
A
K
K
V
G
S
Q
L
E
R
F
H
S
Maize
Zea mays
Rice
Oryza sativa
Thale Cress
Arabidopsis thaliana
NP_200632
180
20382
S92
L
T
A
Q
K
V
G
S
K
L
E
T
F
H
N
Baker's Yeast
Sacchar. cerevisiae
P49775
206
23523
R69
K
T
L
Q
L
I
H
R
F
I
K
W
Q
Y
K
Red Bread Mold
Neurospora crassa
Conservation
Percent
Protein Identity:
100
44.2
94.6
N.A.
N.A.
89.3
86.6
N.A.
70
79
76.3
76
N.A.
N.A.
N.A.
N.A.
N.A.
Protein Similarity:
100
44.2
95.3
N.A.
N.A.
92.6
92
N.A.
76.8
87.1
84.4
83.3
N.A.
N.A.
N.A.
N.A.
N.A.
P-Site Identity:
100
0
93.3
N.A.
N.A.
86.6
86.6
N.A.
80
66.6
53.3
60
N.A.
N.A.
N.A.
N.A.
N.A.
P-Site Similarity:
100
0
93.3
N.A.
N.A.
86.6
86.6
N.A.
93.3
73.3
66.6
73.3
N.A.
N.A.
N.A.
N.A.
N.A.
Percent
Protein Identity:
39.2
N.A.
N.A.
43.8
31
N.A.
Protein Similarity:
53.5
N.A.
N.A.
58.8
46.6
N.A.
P-Site Identity:
26.6
N.A.
N.A.
33.3
13.3
N.A.
P-Site Similarity:
60
N.A.
N.A.
60
46.6
N.A.
Phosphosite
Consensus
Position
-7
-6
-5
-4
-3
-4
-5
0
+1
+2
+3
+4
+5
+6
+7
% Ala:
0
0
25
0
0
0
9
0
9
0
0
0
0
0
0
% A
% Cys:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
9
% C
% Asp:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% D
% Glu:
0
0
0
0
0
0
0
0
0
0
84
0
0
0
0
% E
% Phe:
9
0
0
0
0
0
0
0
9
0
0
0
17
67
0
% F
% Gly:
0
0
0
0
0
0
67
0
0
0
0
0
0
0
9
% G
% His:
0
0
0
0
0
0
9
0
0
0
0
0
67
17
17
% H
% Ile:
0
0
0
0
0
9
0
0
0
17
0
0
0
0
0
% I
% Lys:
9
0
0
9
34
0
0
0
9
0
9
59
0
0
9
% K
% Leu:
9
0
9
0
9
0
0
0
0
17
0
0
0
0
0
% L
% Met:
9
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% M
% Asn:
0
0
0
0
0
0
0
17
0
0
0
0
0
0
17
% N
% Pro:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% P
% Gln:
42
0
0
84
0
0
0
0
17
0
0
0
9
0
25
% Q
% Arg:
9
0
0
0
50
0
0
9
0
0
0
9
0
0
0
% R
% Ser:
0
0
0
0
0
0
9
34
0
0
0
9
0
0
9
% S
% Thr:
9
67
50
0
0
0
0
34
0
0
0
9
0
0
0
% T
% Val:
0
25
9
0
0
84
0
0
50
59
0
0
0
0
0
% V
% Trp:
0
0
0
0
0
0
0
0
0
0
0
9
0
0
0
% W
% Tyr:
0
0
0
0
0
0
0
0
0
0
0
0
0
9
0
% Y
% Spaces:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% _